General
Population: Between 190 and 230 million*
- Medicine: Galen records plague
Pausanian records a description of the skeleton of the her Ajax (probably fossil mastodon or rhinoceros)
Galen writes key medical text
- Deaths: Emperor Pius, Marcus Aurelius of Rome
Africa
- First African Christians martyred at Scillium
Europe
- General: Rugiland peoples - Germanic tribe in Germany, Norway, and Italy - first mentioned
- Roman Empire: Death of Emperor Marcus Aurelius and Pax Romana
Commodus becomes emperor
End of Antoine Plague killing 5 million
- Scotland: Romans defeated and return to Hadrian's wall
Middle East
- Syria: End pf Plague of Galen